M17-02: Immunotherapy of extensive stage small cell lung cancer with dendritic cell based p53 vaccine

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Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer.

PURPOSE The initial goal of this study was to test the immunologic and clinical effects of a new cancer vaccine consisting of dendritic cells (DC) transduced with the full-length wild-type p53 gene delivered via an adenoviral vector in patients with extensive stage small cell lung cancer. EXPERIMENTAL DESIGN Twenty-nine patients with extensive stage small cell lung cancer were vaccinated repe...

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2007

ISSN: 1556-0864

DOI: 10.1097/01.jto.0000282976.88618.ff